Gene Set: BIOCARTA_IL3_PATHWAY

Standard name BIOCARTA_IL3_PATHWAY
Systematic name M17681
Brief description IL 3 signaling pathway
Full description or abstract Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding to its receptor. The receptor for IL-3 is a heterodimer with a ligand-specific alpha chain (70 kD, CD123) and a common beta chain (shared with IL-5 and GM-CSF). Signaling is believed to be primarily through Stat5 and the MAPK pathways.
Collection C2: curated gene sets
      CP:BIOCARTA: BioCarta gene sets
Source publication  
Exact source  
Related gene sets  
External links http://cgap.nci.nih.gov/Pathways/BioCarta/h_il3Pathway
http://cgap.nci.nih.gov/Genes/PathGeneQuery?PAGE=1&ORG=Hs&PATH=h_il3Pathway
Organism Homo sapiens
Contributed by BioCarta
Source platform EntrezGeneIds
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps (show collections to investigate for overlap with this gene set)
Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 15 genes
Gene families Categorize these 15 genes by gene family
Show members (show 15 members mapped to 15 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.