Gene Set: BRCA1_DN.V1_UP

Standard name BRCA1_DN.V1_UP
Systematic name M2748
Brief description Genes up-regulated in MCF10A cells (breast cancer) upon knockdown of BRCA1 [GeneID=672] gene by RNAi.
Full description or abstract MCF10A cells in 3-D culture for 15 h after treatment with BRCA1-RNAi vs Luc-RNAi adenovirus
Collection C6: oncogenic signatures
Source publication Pubmed 16843262   Authors: Furuta S,Wang JM,Wei S,Jeng YM,Jiang X,Gu B,Chen PL,Lee EY,Lee WH
Exact source BRCA1 KD vs LUC KD; top 150 genes (diff. of means)
Related gene sets (show 3 additional gene sets from the source publication)

(show 3 gene sets from the same authors)
External links  
Organism Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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