Gene Set: CRX_DN.V1_DN

Standard name CRX_DN.V1_DN
Systematic name M2792
Brief description Genes down-regulated in retina cells from CRX [GeneID=1406] knockout mice.
Full description or abstract Complete microarray datasets for wild-type vs. Crx-/- comparison at P21 are in Supplementary Table S5. This table contains the full microarray datasets from six microarray hybridizations (three biological replicates each from wild-type (129S6/SvEv) and Crx-/- retinas at P21). The data from each of the individual microarray experiments are labeled with the following prefixes:Crx-mut_#1i etc. and129-wt-P21-#1i etc.
Collection C6: oncogenic signatures
Source publication Pubmed 17653270   Authors: Hsiau TH,Diaconu C,Myers CA,Lee J,Cepko CL,Corbo JC
Exact source Crx-/- mouse retina cells vs Controls; bottom 150 genes (diff. of means)
Related gene sets (show 5 additional gene sets from the source publication)

(show 78 gene sets from the same authors)
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Organism Mus musculus
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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