Gene Set: EIF4E_UP

Standard name EIF4E_UP
Systematic name M2791
Brief description Genes up-regulated in HMEC cells (primary mammary epithelium) upon over-expression of EIF4E [GeneID=1977] gene.
Full description or abstract Translation initiation factor 4E confers primary human cells with neoplastic properties. A comparison of HMEC/hTERT and HMEC/hTERT/eIF4E cells using both total and polyribosoaml associated RNA.
Collection C6: oncogenic signatures
Source publication Pubmed 17638893   Authors: Larsson O,Li S,Issaenko OA,Avdulov S,Peterson M,Smith K,Bitterman PB,Polunovsky VA
Exact source overexpression of eIFGI vs control; top 100 genes (diff. of means)
Related gene sets (show 1 additional gene sets from the source publication)

(show 89 gene sets from the same authors)
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Organism Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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