Gene Set: GO_ANAPHASE_PROMOTING_COMPLEX

Standard name GO_ANAPHASE_PROMOTING_COMPLEX
Systematic name M17133
Brief description A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0005680
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005680
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 22 genes
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Version history 5.2: First introduced

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