Gene Set: GO_BETA_CATENIN_DESTRUCTION_COMPLEX

Standard name GO_BETA_CATENIN_DESTRUCTION_COMPLEX
Systematic name M17464
Brief description A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0030877
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0030877
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 14 genes
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Show members (show 14 members mapped to 14 genes)
Version history 5.2: First introduced

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