Gene Set: GO_COP9_SIGNALOSOME

Standard name GO_COP9_SIGNALOSOME
Systematic name M17460
Brief description A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0008180
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0008180
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 34 genes
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Show members (show 34 members mapped to 34 genes)
Version history 5.2: First introduced

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