Gene Set: GO_CYTOPLASMIC_DYNEIN_COMPLEX

Standard name GO_CYTOPLASMIC_DYNEIN_COMPLEX
Systematic name M17475
Brief description Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0005868
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005868
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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Version history 5.2: First introduced

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