Gene Set: GO_ERBB2_SIGNALING_PATHWAY

Standard name GO_ERBB2_SIGNALING_PATHWAY
Systematic name M11834
Brief description A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.
Full description or abstract  
Collection C5: GO gene sets
      BP: GO biological process
Source publication  
Exact source GO:0038128
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0038128
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 39 genes
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Version history 5.2: First introduced

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