Gene Set: GO_EXECUTION_PHASE_OF_APOPTOSIS

Standard name GO_EXECUTION_PHASE_OF_APOPTOSIS
Systematic name M15953
Brief description A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
Full description or abstract  
Collection C5: GO gene sets
      BP: GO biological process
Source publication  
Exact source GO:0097194
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0097194
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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Version history 5.2: First introduced

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