Gene Set: GO_FANCONI_ANAEMIA_NUCLEAR_COMPLEX

Standard name GO_FANCONI_ANAEMIA_NUCLEAR_COMPLEX
Systematic name M17146
Brief description A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0043240
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0043240
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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Version history 5.2: First introduced

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