Gene Set: GO_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX

Standard name GO_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX
Systematic name M17549
Brief description A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0005942
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005942
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
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Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
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Version history 5.2: First introduced

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