Gene Set: GO_SIN3_COMPLEX

Standard name GO_SIN3_COMPLEX
Systematic name M17382
Brief description A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.
Full description or abstract  
Collection C5: GO gene sets
      CC: GO cellular component
Source publication  
Exact source GO:0016580
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0016580
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform EntrezGeneIds
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps (show collections to investigate for overlap with this gene set)
Compendia expression profiles Human tissue compendium (Novartis)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 13 genes
Gene families Categorize these 13 genes by gene family
Show members (show 13 members mapped to 13 genes)
Version history 5.2: First introduced

See MSigDB license terms here. Please note that certain gene sets have special access terms.