Gene Set: JAK_STAT_CASCADE

Standard name JAK_STAT_CASCADE
Systematic name M11564
Brief description Genes annotated by the GO term GO:0007259. The processes by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
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Collection ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks.
      C5_BP: Archived GO biological process
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External links http://amigo.geneontology.org/amigo/term/GO:0007259
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform HUMAN_GENE_SYMBOL
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Version history 5.2: Archived

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