Human Gene Set: JAK_STAT_CASCADE


Standard name JAK_STAT_CASCADE
Systematic name M11564
Brief description Genes annotated by the GO term GO:0007259. The processes by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
Full description or abstract  
Collection ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks
      C5_GO: ARCHIVED Gene Ontology
            C5_GO:BP: ARCHIVED GO Biological Process
Source publication  
Exact source GO:0007259
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0007259
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references  
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Show members (show 31 source identifiers mapped to 31 genes)
Version history 5.2: Archived

Gene set replaced by GOBP_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT

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