Gene Set: RECEPTOR_MEDIATED_ENDOCYTOSIS

Standard name RECEPTOR_MEDIATED_ENDOCYTOSIS
Systematic name M18488
Brief description Genes annotated by the GO term GO:0006898. The uptake of external materials by cells, utilizing receptors to ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
Full description or abstract  
Collection ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks.
      C5_BP: Archived GO biological process
Source publication  
Exact source  
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0006898
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps
Compendia expression profiles
Advanced query
Gene families
Show members (show 33 members mapped to 33 genes)
Version history 5.2: Archived

See MSigDB license terms here. Please note that certain gene sets have special access terms.