Human Gene Set: RAMALHO_STEMNESS_DN

For the Mouse gene set with the same name, see RAMALHO_STEMNESS_DN

Standard name RAMALHO_STEMNESS_DN
Systematic name M12763
Brief description Genes depleted in embryonic, neural and hematopoietic stem cells.
Full description or abstract The transcriptional profiles of mouse embryonic, neural, and hematopoietic stem cells were compared to define a genetic program for stem cells. A total of 216 genes are enriched in all three types of stem cells, and several of these genes are clustered in the genome. When compared to differentiated cell types, stem cells express a significantly higher number of genes (represented by expressed sequence tags) whose functions are unknown. Embryonic and neural stem cells have many similarities at the transcriptional level. These results provide a foundation for a more detailed understanding of stem cell biology.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 12228720   Authors: Ramalho-Santos M,Yoon S,Matsuzaki Y,Mulligan RC,Melton DA
Exact source Supll. Database
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(show 3 gene sets from the same authors)
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Source species Mus musculus
Contributed by John Newman (University of Washington)
Source platform or
identifier namespace		 AFFY_MG_U74
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Version history 3.0: Renamed from STEMCELL_COMMON_DN

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