DatasetDiabetes_collapsed.gct
PhenotypeNGT
GeneSetC2.symbols.gmt#VOXPHOS
Enrichment Score (ES)0.6227182
Normalized Enrichment Score (NES)1.9482467
Nominal p-value0.006772009
FDR q-value0.029732656
FWER p-Value0.058
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1NDUFA2NDUFA2
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa870.4590.0224Yes
2NDUFB2NDUFB2
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa1020.4460.0488Yes
3COX7A1COX7A1
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)1230.4320.0740Yes
4ATP5EATP5E
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit1590.4090.0968Yes
5NDUFB6NDUFB6
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa1650.4060.1214Yes
6ATP5OATP5O
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)2170.3920.1421Yes
7NDUFB8NDUFB8
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa2390.3870.1645Yes
8NDUFB1NDUFB1
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa2440.3850.1878Yes
9QP-CQP-C
StanfordSource,  GeneCards
low molecular mass ubiquinone-binding protein (9.5kD)2700.3770.2093Yes
10NDUFS5NDUFS5
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)2910.3720.2309Yes
11COX7CCOX7C
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIIc3630.3530.2479Yes
12COX7BCOX7B
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIIb3660.3530.2694Yes
13UQCRUQCR
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase (6.4kD) subunit3760.3500.2903Yes
14ATP5LATP5L
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g3910.3480.3108Yes
15ATP5IATP5I
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e4140.3420.3303Yes
16NDUFA7NDUFA7
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa4840.3300.3460Yes
17COX7A2COX7A2
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)5570.3170.3607Yes
18NDUFA10NDUFA10
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa8170.2890.3611Yes
19NDUFS6NDUFS6
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)9190.2800.3716Yes
20NDUFS8NDUFS8
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)9400.2780.3873Yes
21UQCRBUQCRB
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase binding protein10220.2700.3985Yes
22COX6CCOX6C
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIc11150.2630.4085Yes
23NDUFC1NDUFC1
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa11200.2620.4244Yes
24NDUFA6NDUFA6
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa11260.2620.4401Yes
25COX7A2LCOX7A2L
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIIa polypeptide 2 like11860.2570.4520Yes
26ATP5J2ATP5J2
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 212060.2550.4664Yes
27NDUFA3NDUFA3
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa12090.2550.4819Yes
28HSPC051HSPC051
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase complex (7.2 kD)12330.2540.4960Yes
29ATP5HATP5H
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d12750.2500.5086Yes
30NDUFB5NDUFB5
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa13720.2440.5172Yes
31COX6A1COX6A1
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIa polypeptide 115200.2330.5217Yes
32NGFRAP1NGFRAP1
StanfordSource,  GeneCards
nerve growth factor receptor (TNFRSF16) associated protein 115280.2330.5355Yes
33NDUFAB1NDUFAB1
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa15720.2290.5467Yes
34SDHCSDHC
StanfordSource,  GeneCards
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa16960.2200.5521Yes
35CYC1CYC1
StanfordSource,  GeneCards
cytochrome c-117510.2170.5618Yes
36ATP5F1ATP5F1
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 117700.2160.5739Yes
37NDUFA8NDUFA8
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa17800.2160.5866Yes
38COX4I1COX4I1
StanfordSource,  GeneCards
cytochrome c oxidase subunit IV isoform 121390.1960.5747Yes
39NDUFA4NDUFA4
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa21810.1940.5838Yes
40SDHBSDHB
StanfordSource,  GeneCards
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)22220.1920.5930Yes
41NDUFS7NDUFS7
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)22550.1910.6025Yes
42COX11COX11
StanfordSource,  GeneCards
COX11 homolog, cytochrome c oxidase assembly protein (yeast)23170.1880.6100Yes
43PET112LPET112L
StanfordSource,  GeneCards
PET112-like (yeast)23290.1870.6207Yes
44ATP5DATP5D
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit25240.1780.6187Yes
45UQCRHUQCRH
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase hinge protein26680.1700.6196Yes
46NDUFS4NDUFS4
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)27750.1660.6227Yes
47COX5BCOX5B
StanfordSource,  GeneCards
cytochrome c oxidase subunit Vb31390.1500.6077No
48NDUFB7NDUFB7
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa32950.1440.6062No
49NDUFB3NDUFB3
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa34040.1410.6077No
50UQCRFS1UQCRFS1
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 134110.1410.6159No
51GRIM19GRIM19
StanfordSource,  GeneCards
cell death-regulatory protein GRIM1941910.1110.5707No
52ATP5G3ATP5G3
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 342320.1100.5748No
53SURF1SURF1
StanfordSource,  GeneCards
surfeit 142760.1080.5786No
54ATP5G1ATP5G1
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 144350.1030.5744No
55ATP5JATP5J
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F645190.1010.5750No
56COX10COX10
StanfordSource,  GeneCards
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)45490.1000.5792No
57CYCSCYCS
StanfordSource,  GeneCards
cytochrome c, somatic46470.0960.5787No
58ATP5C1ATP5C1
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 150160.0860.5594No
59COX5ACOX5A
StanfordSource,  GeneCards
cytochrome c oxidase subunit Va50290.0860.5638No
60CYB5CYB5
StanfordSource,  GeneCards
cytochrome b-555320.0700.5346No
61SURF2SURF2
StanfordSource,  GeneCards
surfeit 257680.0630.5228No
62COX15COX15
StanfordSource,  GeneCards
COX15 homolog, cytochrome c oxidase assembly protein (yeast)57850.0630.5256No
63CNOT7CNOT7
StanfordSource,  GeneCards
CCR4-NOT transcription complex, subunit 758960.0590.5219No
64NDUFS2NDUFS2
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)61900.0500.5054No
65NDUFS3NDUFS3
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)63630.0450.4967No
66NDUFA5NDUFA5
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa63740.0450.4988No
67NDUFA9NDUFA9
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa69220.0300.4641No
68MBD3MBD3
StanfordSource,  GeneCards
methyl-CpG binding domain protein 369740.0290.4624No
69SDHDSDHD
StanfordSource,  GeneCards
succinate dehydrogenase complex, subunit D, integral membrane protein73560.0180.4381No
70UQCRC2UQCRC2
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase core protein II74030.0160.4360No
71NDUFC2NDUFC2
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa8421-0.0130.3689No
72NDUFS1NDUFS1
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)8811-0.0240.3443No
73ATP5G2ATP5G2
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 28920-0.0270.3388No
74ATP5BATP5B
StanfordSource,  GeneCards
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide9051-0.0310.3320No
75COX6A2COX6A2
StanfordSource,  GeneCards
cytochrome c oxidase subunit VIa polypeptide 210177-0.0670.2610No
76NDUFB4NDUFB4
StanfordSource,  GeneCards
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa10558-0.0800.2406No
77BCL2L1BCL2L1
StanfordSource,  GeneCards
BCL2-like 110708-0.0850.2358No
78ZNF183ZNF183
StanfordSource,  GeneCards
zinc finger protein 183 (RING finger, C3HC4 type)10835-0.0900.2330No
79CKAP1CKAP1
StanfordSource,  GeneCards
cytoskeleton associated protein 110902-0.0920.2342No
80BCS1LBCS1L
StanfordSource,  GeneCards
BCS1-like (yeast)11531-0.1140.1993No
81SDHASDHA
StanfordSource,  GeneCards
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)12501-0.1560.1442No
82UQCRC1UQCRC1
StanfordSource,  GeneCards
ubiquinol-cytochrome c reductase core protein I12601-0.1610.1475No
83LOC56901LOC56901
StanfordSource,  GeneCards
NADH:ubiquinone oxidoreductase MLRQ subunit homolog14104-0.2660.0635No
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Diabetes_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for VOXPHOS   
Histogram of random enrichment scores (real ES = 0.6227182 )