DatasetDiabetes_collapsed.gct
PhenotypeNGT
GeneSetC2.symbols.gmt#tollPathway
Enrichment Score (ES)0.35742837
Normalized Enrichment Score (NES)1.2974914
Nominal p-value0.10706638
FDR q-value1.0
FWER p-Value0.998
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1SITPECSITPEC
StanfordSource,  GeneCards
likely ortholog of mouse signaling intermediate in Toll pathway-evolutionarily conserved70.6420.1572Yes
2TLR7TLR7
StanfordSource,  GeneCards
toll-like receptor 78710.2840.1694Yes
3TLR3TLR3
StanfordSource,  GeneCards
toll-like receptor 39900.2740.2287Yes
4LY96LY96
StanfordSource,  GeneCards
lymphocyte antigen 9610830.2650.2877Yes
5ELK1ELK1
StanfordSource,  GeneCards
ELK1, member of ETS oncogene family11680.2590.3456Yes
6IKBKBIKBKB
StanfordSource,  GeneCards
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta17870.2160.3574Yes
7TOLLIPTOLLIP
StanfordSource,  GeneCards
toll interacting protein31890.1480.3006No
8MAPK14MAPK14
StanfordSource,  GeneCards
mitogen-activated protein kinase 1442140.1100.2595No
9NFKB1NFKB1
StanfordSource,  GeneCards
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)47410.0940.2476No
10MAP3K14MAP3K14
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase kinase 1448420.0910.2632No
11MYD88MYD88
StanfordSource,  GeneCards
myeloid differentiation primary response gene (88)54750.0710.2386No
12MAP3K7IP2MAP3K7IP2
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase kinase 7 interacting protein 256710.0660.2419No
13CD14CD14
StanfordSource,  GeneCards
CD14 antigen63790.0450.2058No
14MAP2K3MAP2K3
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase 364070.0440.2149No
15MAP2K4MAP2K4
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase 466490.0380.2081No
16JUNJUN
StanfordSource,  GeneCards
v-jun sarcoma virus 17 oncogene homolog (avian)66970.0360.2139No
17TLR2TLR2
StanfordSource,  GeneCards
toll-like receptor 268840.0310.2091No
18MAPK8MAPK8
StanfordSource,  GeneCards
mitogen-activated protein kinase 870180.0270.2070No
19IKBKGIKBKG
StanfordSource,  GeneCards
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma74310.0160.1834No
20FOSFOS
StanfordSource,  GeneCards
v-fos FBJ murine osteosarcoma viral oncogene homolog77120.0080.1667No
21MAP3K7MAP3K7
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase kinase 778500.0040.1585No
22NFKBIANFKBIA
StanfordSource,  GeneCards
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha8112-0.0040.1420No
23TLR6TLR6
StanfordSource,  GeneCards
toll-like receptor 68201-0.0070.1378No
24IRAK1IRAK1
StanfordSource,  GeneCards
interleukin-1 receptor-associated kinase 19640-0.0490.0541No
25CHUKCHUK
StanfordSource,  GeneCards
conserved helix-loop-helix ubiquitous kinase9958-0.0590.0475No
26MAP3K1MAP3K1
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase kinase 110474-0.0770.0323No
27TRAF6TRAF6
StanfordSource,  GeneCards
TNF receptor-associated factor 610587-0.0810.0447No
28PRKRPRKR
StanfordSource,  GeneCards
protein kinase, interferon-inducible double stranded RNA dependent10626-0.0820.0624No
29RELARELA
StanfordSource,  GeneCards
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)11053-0.0970.0579No
30TLR4TLR4
StanfordSource,  GeneCards
toll-like receptor 411999-0.1330.0276No
31MAP3K7IP1MAP3K7IP1
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase kinase 7 interacting protein 113086-0.1890.0017No
32MAP2K6MAP2K6
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase 613919-0.2490.0075No
33PPARAPPARA
StanfordSource,  GeneCards
peroxisome proliferative activated receptor, alpha14193-0.2770.0574No
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Diabetes_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for tollPathway   
Histogram of random enrichment scores (real ES = 0.35742837 )