Syzygy - SNP and indel calling for pooled and individual targeted resequencing studies.

In the News

October 9, 2011. Rare variants and Inflammatory Bowel Disease.

April 15, 2011.    Syzygy release version 1.1.0 is now available. 

April 15, 2011.    C-alpha Test manuscript is published in PLoS Genetics.

September 30, 2010.    NextGenSeq@Nature highlights pooled sequencing for complex I deficiency. 

September 23, 2010.  Pooled sequencing for complex I deficiency.



What is Syzygy?

 Syzygy is a targeted sequencing post processing analysis tool that allows:

  • SNP and indel detection
  • Allele frequency estimation
  • Single-marker association test
  • Group-wise marker test association
  • Experimental QC summary (%dbSNP, Ts/Tv, Ns/S)
  • Power to detect variant 

Download Software


Syzygy software is available for download here.





User Guide available for download.