Difference between revisions of "Gsea papers"

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These are papers in which GSEA / Kolmogorov-Smirnov statistics were used.  They are illustrative of the kinds of applications of the methodology.<br />An up-to-date listing of Broad Cancer Genomics publications is available [[http://somethinbg]]<br /><br />        Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A.,        Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S. &amp; Mesirov, J. P.        (2005) Proc. Natl. Acad. Sci. USA 102, 15545-15550.        <strong>Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression            profiles.<br /><br /></strong>        Andrea Bild and Phillip George Febbo        PNAS | October 25, 2005 | vol. 102 | no. 43 | 15278-15279        <strong>COMMENTARY: Application of a priori established gene sets to discover biologically important            differential expression in microarray data</strong><br /><br />Lamb, J., Ramaswamy, S.,        Ford, H. L., Contreras, B., Martinez, R. V., Kittrell, F. S., Zahnow, C.        A., Patterson, N., Golub, T. R., and Ewen, M. E. (2003). <strong>A mechanism of        cyclin D1 action encoded in the patterns of gene expression in human        cancer. </strong>Cell<em> 114</em>, 323-334.<br /><br />Mootha, V. K., Lindgren, C.        M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver,        P., Carlsson, E., Ridderstrale, M., Laurila, E.<em>, et al.</em> (2003). <strong>        PGC-1alpha-responsive genes involved in oxidative phosphorylation are        coordinately downregulated in human diabetes. </strong>Nat Genet<em> 34</em>,        267-273.<br /><br />Monti, S., Savage, K. J.,        Kutok, J. L., Feuerhake, F., Kurtin, P., Mihm, M., Wu, B., Pasqualucci,        L., Neuberg, D., Aguiar, R. C.<em>, et al.</em> (2004). <strong>Molecular        profiling of diffuse large B-cell lymphoma identifies robust subtypes        including one characterized by host inflammatory response.</strong> Blood.
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These are papers in which GSEA / Kolmogorov-Smirnov statistics were used.  They are illustrative of the kinds of applications of the methodology.<br />An up-to-date listing of Broad Cancer Genomics publications is available [http://www.broad.mit.edu/cgi-bin/cancer/publications/pub_menu.cgi here]<br /><br />        Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A.,        Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S. &amp; Mesirov, J. P.        (2005) Proc. Natl. Acad. Sci. USA 102, 15545-15550.        <strong>Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression            profiles.<br /><br /></strong>        Andrea Bild and Phillip George Febbo        PNAS | October 25, 2005 | vol. 102 | no. 43 | 15278-15279        <strong>COMMENTARY: Application of a priori established gene sets to discover biologically important            differential expression in microarray data</strong><br /><br />Lamb, J., Ramaswamy, S.,        Ford, H. L., Contreras, B., Martinez, R. V., Kittrell, F. S., Zahnow, C.        A., Patterson, N., Golub, T. R., and Ewen, M. E. (2003). <strong>A mechanism of        cyclin D1 action encoded in the patterns of gene expression in human        cancer. </strong>Cell<em> 114</em>, 323-334.<br /><br />Mootha, V. K., Lindgren, C.        M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver,        P., Carlsson, E., Ridderstrale, M., Laurila, E.<em>, et al.</em> (2003). <strong>        PGC-1alpha-responsive genes involved in oxidative phosphorylation are        coordinately downregulated in human diabetes. </strong>Nat Genet<em> 34</em>,        267-273.<br /><br />Monti, S., Savage, K. J.,        Kutok, J. L., Feuerhake, F., Kurtin, P., Mihm, M., Wu, B., Pasqualucci,        L., Neuberg, D., Aguiar, R. C.<em>, et al.</em> (2004). <strong>Molecular        profiling of diffuse large B-cell lymphoma identifies robust subtypes        including one characterized by host inflammatory response.</strong> Blood.

Revision as of 01:14, 15 March 2006

These are papers in which GSEA / Kolmogorov-Smirnov statistics were used. They are illustrative of the kinds of applications of the methodology.
An up-to-date listing of Broad Cancer Genomics publications is available here

Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S. & Mesirov, J. P. (2005) Proc. Natl. Acad. Sci. USA 102, 15545-15550. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles.

Andrea Bild and Phillip George Febbo PNAS | October 25, 2005 | vol. 102 | no. 43 | 15278-15279 COMMENTARY: Application of a priori established gene sets to discover biologically important differential expression in microarray data

Lamb, J., Ramaswamy, S., Ford, H. L., Contreras, B., Martinez, R. V., Kittrell, F. S., Zahnow, C. A., Patterson, N., Golub, T. R., and Ewen, M. E. (2003). A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. Cell 114, 323-334.

Mootha, V. K., Lindgren, C. M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstrale, M., Laurila, E., et al. (2003). PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34, 267-273.

Monti, S., Savage, K. J., Kutok, J. L., Feuerhake, F., Kurtin, P., Mihm, M., Wu, B., Pasqualucci, L., Neuberg, D., Aguiar, R. C., et al. (2004). Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood.