MSigDB v5.2 Release Notes

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This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).

C2: Curated gene sets (+4)

• CGP: chemical and genetic perturbations (+4 gene sets).
• CP: canonical pathways.

C5: GO gene sets (+4712)

Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.

This collection is divided into three subcollections:

• CC: GO Cellular component (+584 gene sets). Gene sets derived from the Cellular Component Ontology.
• MF: GO Molecular function (+929 gene sets). Gene sets derived from the Molecular Function Ontology.
• BP: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.

C6 gene sets

Corrected typing errors in the names of two gene sets.

C7 gene sets

Corrected typing errors in the names of 332 gene sets and fixed other errors in gene set annotations.

For more information

For complete descriptions of all collections or to download the updated gene sets, go to the Browse Collections page. Detailed information about v5.1 MSigDB gene sets that have been renamed, deprecated or archived in the 5.2 release can be found here