Difference between revisions of "GSEA v2.08. Release Notes"

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[http://www.broadinstitute.org/gsea/ GSEA Home] |
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[http://www.broadinstitute.org/gsea/downloads.jsp Downloads] |
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[http://www.broadinstitute.org/gsea/msigdb/ Molecular Signatures Database] |
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[http://www.broadinstitute.org/cancer/software/gsea/wiki/index.php/Main_Page Documentation] |
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[http://www.broadinstitute.org/gsea/contact.jsp Contact] <br />
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<br />
 
<p>In release 2.0.8, there is <strong>no change</strong>  to the GSEA algorithm.</p>
 
<p>In release 2.0.8, there is <strong>no change</strong>  to the GSEA algorithm.</p>
 
<p>The changes include:</p>
 
<p>The changes include:</p>
 
<ol>
 
<ol>
<li>Browser support for MSigDB database v3.1.
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<li>When you Browse MSigDB, by default it will now display version 3.1 of the MSigDB gene sets.  
<p>To browse MSigDB v3.0 or v2.5, type <font color="red">msigdb_v3.xml</font> or <font color="red">msigdb_v2.5.xml</font> in the <em>File path or URL to the MSigDB database</em> and click the <em>Load database</em> button.</p>
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<p>To browse earlier versions of MSigDB, type <strong>msigdb_v3.xml</strong> or <strong>msigdb_v2.5.xml</strong> in the <em>File path or URL to the MSigDB database</em> and click the <em>Load database</em> button.</p>
 
<p>[[Image:Loading MSigDB3.1.jpg]]</p>
 
<p>[[Image:Loading MSigDB3.1.jpg]]</p>
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<br>
 
</li>
 
</li>
<li>Browser support for the <strong>C6</strong> collection - Oncogenic Signatures.
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<li><p>In the previous version of GSEA, there were display issues when viewing the selection menu of GMT files in the MSigDB database from the <em>Run Gsea</em> screen and the <em>Chip2Chip mapping</em> screen. These issues have been fixed. The GMT files for the latest release of MSigDB are now always displayed at the top of the list and in a bold font.</p>
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<p>[[Image:Viewing_GMT_files.png]]</p>
 
</li>
 
</li>
<li>Fix issues with display, font and ordering of gene set GMT files.
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<li><p>The latest version of MSigDB is significantly larger than previous versions and we now recommend that you run GSEA with no less than 1 GB of memory. If you run GSEA from the command line, use the -Xmx Java option to specify increased heap size. For example, <tt>java -Xmx1024m -jar gsea2-2.08.jar</tt>.</p>
<p>The Gene sets database selection menu from the Run GSEA Page now lists GMT files in decreasing order of MSigDB version. Files corresponding to the latest version appear at the top and in a bold font.  Within MSigDB release versions, the files are in increasing order of collection numbers. Within collections, collection subtypes are in alphabetic order.  As seen in the screenshot below, all files are now in black and no longer reveal the entire FTP path, making the dialog window easier to use.</p>
 
<p>[[Image:Viewing GMT files.jpg]]</p>
 
 
</li>
 
</li>
 
</ol>
 
</ol>

Latest revision as of 03:16, 25 September 2016

GSEA Home | Downloads | Molecular Signatures Database | Documentation | Contact

In release 2.0.8, there is no change to the GSEA algorithm.

The changes include:

  1. When you Browse MSigDB, by default it will now display version 3.1 of the MSigDB gene sets.

    To browse earlier versions of MSigDB, type msigdb_v3.xml or msigdb_v2.5.xml in the File path or URL to the MSigDB database and click the Load database button.

    Loading MSigDB3.1.jpg


  2. In the previous version of GSEA, there were display issues when viewing the selection menu of GMT files in the MSigDB database from the Run Gsea screen and the Chip2Chip mapping screen. These issues have been fixed. The GMT files for the latest release of MSigDB are now always displayed at the top of the list and in a bold font.

    Viewing GMT files.png

  3. The latest version of MSigDB is significantly larger than previous versions and we now recommend that you run GSEA with no less than 1 GB of memory. If you run GSEA from the command line, use the -Xmx Java option to specify increased heap size. For example, java -Xmx1024m -jar gsea2-2.08.jar.