MSigDB v5.2 Release Notes

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<p>This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).</p>
<p>This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).</p>
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<h3>C2: Curated gene sets (+4)</h3>
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<h2>Updates to C2 collection</h2>
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<h3>C2:CGP curated gene sets</h3>
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    <li><strong>CGP</strong>: chemical and genetic perturbations (+4 gene sets).</li>
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<p>We added 4 gene sets (submitted by Dr. Eppert, MgGill University) and redefined the gene set MCLACHLAN_DENTAL_CARIES_DN</p>
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    <li><strong>CP</strong>: canonical pathways.</li>
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<h2>Overhaul of C5 collection</h2>
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<h3>C5: GO gene sets (+4712)</h3>
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<p> Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.</p>
<p> Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.</p>
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     <li><strong>BP</strong>: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.</li>
     <li><strong>BP</strong>: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.</li>
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<h3>C6 gene sets </h3>
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<h2>Updates to C6 collection</h2>
Corrected typing errors in the names of two gene sets.
Corrected typing errors in the names of two gene sets.
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<h3>C7 gene sets </h3>
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<h2>Updates to C7 collection</h2>
Corrected typing errors in the names of 332 gene sets and fixed other errors in gene set annotations.
Corrected typing errors in the names of 332 gene sets and fixed other errors in gene set annotations.
<h3>For more information</h3>
<h3>For more information</h3>
For complete descriptions of all collections or to download the updated gene sets, go to the [http://www.broad.mit.edu/gsea/msigdb/collections.jsp Browse Collections] page.
For complete descriptions of all collections or to download the updated gene sets, go to the [http://www.broad.mit.edu/gsea/msigdb/collections.jsp Browse Collections] page.
Detailed information about v5.1 MSigDB gene sets that have been renamed, deprecated or archived in the 5.2 release can be found [[Mapping_between_v5.2_and_v5.1_gene_sets|here]]
Detailed information about v5.1 MSigDB gene sets that have been renamed, deprecated or archived in the 5.2 release can be found [[Mapping_between_v5.2_and_v5.1_gene_sets|here]]

Revision as of 19:53, 5 October 2016

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This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).

Contents

Updates to C2 collection

C2:CGP curated gene sets

We added 4 gene sets (submitted by Dr. Eppert, MgGill University) and redefined the gene set MCLACHLAN_DENTAL_CARIES_DN

Overhaul of C5 collection

Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.

This collection is divided into three subcollections:

  • CC: GO Cellular component (+584 gene sets). Gene sets derived from the Cellular Component Ontology.
  • MF: GO Molecular function (+929 gene sets). Gene sets derived from the Molecular Function Ontology.
  • BP: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.

Updates to C6 collection

Corrected typing errors in the names of two gene sets.

Updates to C7 collection

Corrected typing errors in the names of 332 gene sets and fixed other errors in gene set annotations.

For more information

For complete descriptions of all collections or to download the updated gene sets, go to the Browse Collections page. Detailed information about v5.1 MSigDB gene sets that have been renamed, deprecated or archived in the 5.2 release can be found here

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