Difference between revisions of "MSigDB v5.2 Release Notes"
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<p>This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).</p> | <p>This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).</p> | ||
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<li><strong>CP</strong>: canonical pathways.</li> | <li><strong>CP</strong>: canonical pathways.</li> | ||
</ul> | </ul> | ||
| − | <h3>C5: GO gene sets ( | + | <h3>C5: GO gene sets (+4712)</h3> |
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<p> Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.</p> | <p> Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.</p> | ||
<p>This collection is divided into three subcollections:</p> | <p>This collection is divided into three subcollections:</p> | ||
<ul> | <ul> | ||
| − | <li><strong>CC</strong>: GO Cellular component (+ | + | <li><strong>CC</strong>: GO Cellular component (+584 gene sets). Gene sets derived from the Cellular Component Ontology.</li> |
| − | <li><strong>MF</strong>: GO Molecular function (+ | + | <li><strong>MF</strong>: GO Molecular function (+929 gene sets). Gene sets derived from the Molecular Function Ontology.</li> |
| − | <li><strong>BP</strong>: GO Biological process (+ | + | <li><strong>BP</strong>: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.</li> |
</ul> | </ul> | ||
<p> <strong>GSEA users</strong>: Gene set enrichment analysis identifies gene sets consisting of co-regulated genes; GO gene sets are based on ontologies and do not generally consist of co-regulated genes.</p> | <p> <strong>GSEA users</strong>: Gene set enrichment analysis identifies gene sets consisting of co-regulated genes; GO gene sets are based on ontologies and do not generally consist of co-regulated genes.</p> | ||
Revision as of 14:46, 5 October 2016
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This page describes the changes made to the gene set collections for Release 5.2 of the Molecular Signatures Database (MSigDB).
Contents
C2: Curated gene sets (+4)
- CGP: chemical and genetic perturbations (+4 gene sets).
- CP: canonical pathways.
C5: GO gene sets (+4712)
Gene sets in this new collection are derived from the controlled vocabulary of the Gene Ontology (GO) project: The Gene Ontology Consortium. Gene Ontology: tool for the unification of biology. Nature Genet. (2000) 25: 25-29 (http://www.geneontology.org/). The gene sets are named by GO term and contain genes annotated by that term.
This collection is divided into three subcollections:
- CC: GO Cellular component (+584 gene sets). Gene sets derived from the Cellular Component Ontology.
- MF: GO Molecular function (+929 gene sets). Gene sets derived from the Molecular Function Ontology.
- BP: GO Biological process (+4653 gene sets). Gene sets derived from the Biological Process Ontology.
GSEA users: Gene set enrichment analysis identifies gene sets consisting of co-regulated genes; GO gene sets are based on ontologies and do not generally consist of co-regulated genes.
C6 gene sets
C7 gene sets
For more information
For complete descriptions of all collections or to download the updated gene sets, go to the Browse Collections page.
