Since the GATK first started gaining traction in the research community ca. 2010, its development has sustained a fairly rapid pace, with a new major version (1, 2 and 3 so far) coming out about every 2 years. Each major version was a straight continuation of the same codebase, distinguished by significantly new tools and capabilities (e.g. HaplotypeCaller in 2.0, the GVCF workflow in 3.0).

This year, we're on track for a new major version, but we're breaking the mold of the classic GATK codebase. Over the past 18 months, in parallel to the ongoing 3.x development effort, we built a brand new GATK engine that is faster, more scalable and can support new types of analysis that weren't possible in the original GATK framework. Now we're hard at work porting the classic GATK tools over to the new framework, as well as developing some new ones (copy number!). The resulting toolkit will be formally released as GATK 4 later this year. If you're keen to try it out, it's already available as an alpha preview; I'll follow up on this with more details soon.

But that's not all. At the same time, we kept working on the GATK 3.x package in order to continue delivering improvements to the research community. Now we're just about ready to release version 3.6 -- nothing yuuugely different, but quite a few bug fixes and feature enhancements (especially in the GVCF workflow tools) that have been widely requested. Again, details to follow. Oh, and it supports Java 8! Which previous versions do not -- it may look like they do because they run on it without crashing, but there could be silent correctness errors. Which are the worst; I prefer a good honest in-your-face run-busting error any day.

So there you have it; version 3.6 coming out sometime next week (-ish), and GATK 4 coming out later this year, probably Fall timeframe. In between, we'll have one last 3.x release, either a patch release (3.6-x) or a proper minor release (3.7) depending on how substantial are the changes involved, to immortalize the last state of the classic GATK before it gets encased in amber.






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RT @curroortuno: Do you want to learn about sequencing data analysis in an amazing city? Register now at @gatk_dev workshop "From reads to…
3 Sep 19
Thank you @murilocervato for hosting our GATK workshop in Sao Paolo last week! Great group of participants, we’ll s… https://t.co/QbT7P5dw5k
3 Sep 19
@RealMattJM “Convoluted”, huh? We see what you did there... https://t.co/GbnpCFWPOX
29 Aug 19
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28 Aug 19
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30 Jul 19

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Do you want to learn about sequencing data analysis in an amazing city? Register now at @gatk_dev workshop "From re… https://t.co/ISBVX2Xwr5
3 Sep 19
Another successful #GATK workshop in the books! @TerraBioApp @gatk_dev https://t.co/oFzPLei0f9
3 Sep 19
Day 2 of #GATK workshop this time in São Paulo, Brazil! Hands-on tutorials using @TerraBioApp #GATK Best Practices… https://t.co/GgtENDNfhk
28 Aug 19
In spite of their stated mission to support human health through genomics, many GATK pipelines are applicable to no… https://t.co/FKQTouZjbv
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Me: driving myself insane over what data to keep and what to not bother with for thesis and also frantically trying… https://t.co/er2klIcw5i
18 Jul 19

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