The Library of Integrated Cellular Signatures (LINCS) is an NIH program which funds the generation of perturbational profiles across multiple cell and perturbation types, as well as read-outs, at a massive scale.
Coupled with analytical tools, the vision is to, someday, make it possible for researchers to simply "look up" any cellular response in a genome-scale library of cellular signatures.
To date, LINCS has generated over 1 billion data points of perturbational profiles spanning small-molecules and genetic gain- and loss-of-function across multiple cell types.

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